Letters that make mess-up
s, e, p, m, u are letters that make 'mess-up'
1 possible definitions for 'mess-up'
Under this definition, mess-up is a noun and has the following properties:
'mess-up' can be a region of United Kingdom, UK, U.K., Britain, United Kingdom of Great Britain and Northern Ireland, Great Britain
screw up, mess up, botch, bodge, botch up, ball up, muck up, bollix, bollocks up, louse up, foul up, fuck up, fluff, bumble, spoil, blow, mishandle, bollix up, bollocks, fumble, muff, bobble, bungle, flub are derivatives of 'mess-up'.