s, a, b, e, n, c, t, u are letters that make 'substance abuse'
sub, stance, AB, ab, AN, BS, SE, tan, CE, substance, use, abuse, bus, US, NC, Ce, Se, Ta, Ab are words within 'substance abuse'
substance abuser is a word created by adding a letter to 'substance abuse'
1 possible definitions for 'substance abuse'
Under this definition, substance abuse is a noun and has the following properties:
drug abuse, habit have the same meaning as 'substance abuse'
alcohol abuse, alcoholic abuse, alcoholism abuse are types of 'substance abuse'.